https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:55722 Wed 19 Jun 2024 09:33:12 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:42195 Wed 13 Mar 2024 11:21:56 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:26076 Wed 11 Apr 2018 12:55:40 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33733 Wed 09 Feb 2022 15:56:05 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44034 Wed 05 Oct 2022 15:53:23 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27846 90, 60-90, and <60 mL/min/1.73 m², respectively). Outcomes: The effect of admission eGFR on the primary outcome of death or major disability at 90 days (defined as modified Rankin Scale scores of 3-6) was analyzed using a multivariable logistic regression model. Potential effect modification of intensive BP lowering treatment by admission eGFR was assessed by interaction terms. Results: Of 2,623 included participants, 912 (35%) and 280 (11%) had mildly and moderately/severely decreased eGFRs, respectively. Patients with moderately/severely decreased eGFRs had the greatest risk for death or major disability at 90 days (adjusted OR, 1.82; 95% CI, 1.28-2.61). Effects of early intensive BP lowering were consistent across different eGFRs (P = 0.5 for homogeneity). Limitations: Generalizability issues arising from a clinical trial population. Conclusions: Decreased eGFR predicts poor outcome in acute ICH. Early intensive BP lowering provides similar treatment effects in patients with ICH with decreased eGFRs.]]> Thu 09 Dec 2021 11:03:39 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:51367 10-fold higher odds of preterm birth and low birthweight and 1.8- to 4.6-fold increased odds of other adverse outcomes. In transplanted women, mediation analysis revealed that pregnancy-induced hypertension contributed only a modest proportional effect (2.5%–11.2%) on adverse outcomes. Conclusion: Maternal dialysis and transplantation conferred excess perinatal morbidity, particularly for preterm babies, and even in women with good preconception allograft function. Pregnancy-induced hypertension is not the predominant determinant of perinatal morbidity. Preconception counseling of women with kidney disease should encompass discussion of perinatal complications.]]> Thu 02 May 2024 15:48:24 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:8604 Sat 24 Mar 2018 08:39:54 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44556 Mon 17 Oct 2022 10:13:28 AEDT ]]>